Tirzepatide
GLP-1 / metabolic · By Preptide Pro editorial team · Last updated
Tirzepatide is a glp-1 / metabolic peptide, and it has an FDA-approved product. A dual GIP and GLP-1 receptor agonist. Approved by the FDA for type 2 diabetes, chronic weight management and obstructive sleep apnea with obesity.
FDA-approved (see products)Chemistry (PubChem)
| PubChem CID | 166567236 |
|---|---|
| CAS number | 2023788-19-2 |
| Molecular formula | C225H348N48O68 |
| Molecular weight | 4813 g/mol |
| Other names | Tirzepatide, Mounjaro (TN), Zepbound (TN), Tirzepatide free base?, Tirzepatide (JAN/USAN), WLZ4518, BP-43671, D11360 |
Is Tirzepatide FDA-approved?
| Brand | Application | Status | Sponsor |
|---|---|---|---|
| MOUNJARO | NDA215866 | Prescription | ELI LILLY AND CO |
| MOUNJARO KWIKPEN | NDA215866 | Prescription | ELI LILLY AND CO |
| MOUNJARO (AUTOINJECTOR) | NDA215866 | Prescription | ELI LILLY AND CO |
| ZEPBOUND | NDA217806 | Prescription | ELI LILLY AND CO |
| ZEPBOUND KWIKPEN | NDA217806 | Prescription | ELI LILLY AND CO |
| ZEPBOUND (AUTOINJECTOR) | NDA217806 | Prescription | ELI LILLY AND CO |
How much research is there on Tirzepatide?
PubMed lists 2,737 records for “tirzepatide”, of which 148 are tagged as human clinical trials.
| Recent study | Journal | Date |
|---|---|---|
| Baseline monocyte GIP receptor mRNA expression is associated with reductions in body weight and FIB-4 index after switching to tirzepatide in patients with type 2 diabetes. | Diabetol Int | 2027 Jan |
| Food noise: A theoretical review. | Appetite | 2027 Jan 1 |
| GLP-1 receptor biology and the therapeutic role of incretin-based agonists in metabolic diseases. | Eur J Pharmacol | 2026 Dec 10 |
| Tirzepatide alleviates hepatic steatosis and inflammation in MASLD partly through suppression of macrophage Dectin-1/Syk/NF-κB signaling. | Eur J Pharmacol | 2026 Dec 10 |
| 12-month weight-loss trajectories and predictors of response to tirzepatide under individualized dosing: A multicenter real-world study. | Obes Pillars | 2026 Dec |
Sources
This is general research information, not medical advice. Check with a clinician before using any compound.