TB-500 (Thymosin beta-4 fragment)
Tissue repair · By Preptide Pro editorial team · Last updated
TB-500 (Thymosin beta-4 fragment) is a tissue repair peptide, and it is not FDA-approved. A synthetic peptide based on thymosin beta-4, a natural protein involved in cell movement and actin regulation. Studied mainly in animal and lab models of tissue repair.
Not FDA-approvedChemistry (PubChem)
| PubChem CID | 45382195 |
|---|---|
| CAS number | Not listed |
| Molecular formula | C212H350N56O78S |
| Molecular weight | 4963 g/mol |
| Other names | Thymosin Beta 4, THYMOSIN BETA 4 ACETATE, Thymosin beta4 Acetate, Thymosin beta 4?, Thymosin b4 (cattle), orb1910607, AS-75351, PD079485 |
Is TB-500 (Thymosin beta-4 fragment) FDA-approved?
Not FDA-approved. No matching NDA or BLA was found in openFDA (Drugs@FDA).
How much research is there on TB-500 (Thymosin beta-4 fragment)?
PubMed lists 1,038 records for “"thymosin beta-4" OR "thymosin beta 4"”, of which 7 are tagged as human clinical trials.
| Recent study | Journal | Date |
|---|---|---|
| Investigational Peptides in Orthopaedic Practice: Evidence, Safety, and Patient Counseling for BPC-157, Thymosin Beta-4, and TB-500. | J Am Acad Orthop Surg | 2026 Oct 27 |
| Paracrine TMSB4X signaling from oligodendrocytes promotes diffuse glioma dissemination. | Oncogene | 2026 Oct 26 |
| Comparative Transcriptomic Profiling of Diabetic Wound Responses to Recombinant Periplaneta americana Thymosin Isoforms in Male ob/ob Mice. | Genes (Basel) | 2026 Oct 16 |
| Understanding the effects of ciprofloxacin on corneal epithelial cells: a study using electric cell-substrate impedance sensing (ECIS) technology. | Exp Eye Res | 2026 Oct |
| Peptides in Regenerative Medicine: A Comprehensive Review of Clinical Applications in Tissue Repair and Chronic Pain Management. | Curr Pain Headache Rep | 2026 Aug 24 |
Sources
This is general research information, not medical advice. Check with a clinician before using any compound.