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SS-31 (Elamipretide)

Mitochondrial · By Preptide Pro editorial team · Last updated

SS-31 (Elamipretide) is a mitochondrial peptide, and it has an FDA-approved product. A mitochondria-targeting tetrapeptide that binds cardiolipin. It has been studied in clinical trials for rare mitochondrial diseases, and openFDA lists an approved product (see the FDA section).

FDA-approved (see products)

Chemistry (PubChem)

PubChem CID11764719
CAS number736992-21-5
Molecular formulaC32H49N9O5
Molecular weight639.8 g/mol
Other namesElamipretide, bendavia, Ocuvia, MTP-131, MTP 131, SS-31, Szeto-schiller peptide, Elamipretida

Is SS-31 (Elamipretide) FDA-approved?

FDA application records from openFDA
BrandApplicationStatusSponsor
FORZINITYNDA215244PrescriptionSTEALTH BIOTHERAPS

How much research is there on SS-31 (Elamipretide)?

PubMed lists 527 records for “elamipretide OR SS-31”, of which 22 are tagged as human clinical trials.

Most recent PubMed records
Recent studyJournalDate
Pre-qualifications, learning strategies, and study satisfaction among medical students: insights from a multicenter German study.Med Educ Online2026 Dec 31
Seawater immersion reshapes the temporal dynamics of traumatic brain injury and reveals mitochondrial oxidative stress as a modifiable therapeutic target.Exp Neurol2026 Dec
Disruption of hippocampal mitochondrial function underlies opioid-induced postoperative cognitive dysfunction in aged rats.Brain Behav Immun2026 Nov
Report from the 2026 Barth Syndrome Foundation International Scientific, Medical & Family Conference: Advances in Barth Syndrome Research, Therapy Development, and Clinical Care.J Dev Biol2026 Oct 19
Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes.Adv Sci (Weinh)2026 Oct 14

Sources

This is general research information, not medical advice. Check with a clinician before using any compound.

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