Melanotan II
Melanocortin · By Preptide Pro editorial team · Last updated
Melanotan II is a melanocortin peptide, and it is not FDA-approved. A synthetic, non-selective melanocortin receptor agonist related to alpha-MSH. It is not approved, and health agencies have warned about unregulated products.
Not FDA-approvedChemistry (PubChem)
| PubChem CID | 92432 |
|---|---|
| CAS number | 121062-08-6 |
| Molecular formula | C50H69N15O9 |
| Molecular weight | 1024.2 g/mol |
| Other names | Melanotan II, Melanotan-II, RefChem:925444, DTXCID3075626, MT-II, Melanotan (MT)-II, Melatonan, Melanotan II acetate salt |
Is Melanotan II FDA-approved?
Not FDA-approved. No matching NDA or BLA was found in openFDA (Drugs@FDA).
How much research is there on Melanotan II?
PubMed lists 244 records for “"melanotan II" OR "melanotan-II"”, of which 4 are tagged as human clinical trials.
| Recent study | Journal | Date |
|---|---|---|
| Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review. | Sex Med Rev | 2026 Sep 30 |
| Dangers of Injectable Peptides and Other Unregulated "Biohacking" Drugs. | Mo Med | 2026 Jul-Aug |
| Changes in Oral Mucosa Associated with Melanotan II Injections: A Case Report. | Life (Basel) | 2026 Feb 3 |
| Melanotan II nasal spray: a possible risk factor for oral mucosal malignant melanoma? | Int J Oral Maxillofac Surg | 2025 Sep |
| Antidepressant-like and antistress effects of the ACTH(4-10) synthetic analogs Semax and Melanotan II on male rats in a model of chronic unpredictable stress. | Eur J Pharmacol | 2024 Dec 5 |
Sources
This is general research information, not medical advice. Check with a clinician before using any compound.