Humanin
Mitochondrial · By Preptide Pro editorial team · Last updated
Humanin is a mitochondrial peptide, and it is not FDA-approved. A small peptide encoded in mitochondrial DNA. Studied in lab and animal models of cell protection and aging.
Not FDA-approvedChemistry (PubChem)
| PubChem CID | 16131438 |
|---|---|
| CAS number | 330936-69-1 |
| Molecular formula | C119H204N34O32S2 |
| Molecular weight | 2687.2 g/mol |
| Other names | Humanin, RefChem:146895, DTXCID60109240, HUMANIN TRIFLUOROACETATE, formyl humanin, Protein Humanin (human), Humanin, human, 1-24-Protein humanin (human) |
Is Humanin FDA-approved?
Not FDA-approved. No matching NDA or BLA was found in openFDA (Drugs@FDA).
How much research is there on Humanin?
PubMed lists 573 records for “humanin”, of which 9 are tagged as human clinical trials.
| Recent study | Journal | Date |
|---|---|---|
| Mitochondrial-derived peptides and cytoprotection in acute respiratory distress syndrome: emerging therapeutic promise of humanin. | Am J Respir Cell Mol Biol | 2026 Nov 1 |
| Humanin-G protects septic acute respiratory distress syndrome by mediating mitochondrial function in lung vascular endothelial cells. | Am J Respir Cell Mol Biol | 2026 Nov 1 |
| Humanin variants differentially regulate BID fibrilization and suppress BAX- and BID-dependent membrane permeabilization. | J Biol Chem | 2026 Oct 23 |
| Mitochondrial-derived peptides (MDPs) activated by physical exercise as therapeutic targets for metabolic disorders: A systematic review. | Physiol Int | 2026 Oct 16 |
| Humanin attenuates neuronal cellular senescence and preserves neurotransmitter release in differentiated PC12 cells. | Neuroscience | 2026 Oct 12 |
Sources
This is general research information, not medical advice. Check with a clinician before using any compound.