Epitalon
Longevity · By Preptide Pro editorial team · Last updated
Epitalon is a longevity peptide, and it is not FDA-approved. A synthetic tetrapeptide (Ala-Glu-Asp-Gly) modeled on a pineal gland extract. Research comes mostly from a small number of groups, in lab and animal models.
Not FDA-approvedChemistry (PubChem)
| PubChem CID | 219042 |
|---|---|
| CAS number | 307297-39-8 |
| Molecular formula | C14H22N4O9 |
| Molecular weight | 390.35 g/mol |
| Other names | Epitalon, Epithalon, Epithalone, Ala-Glu-Asp-Gly, AE-0 peptide, alanyl-glutamyl-aspartyl-glycine, RefChem:921052, DTXCID801381023 |
Is Epitalon FDA-approved?
Not FDA-approved. No matching NDA or BLA was found in openFDA (Drugs@FDA).
How much research is there on Epitalon?
PubMed lists 144 records for “epitalon OR epithalon”, of which 1 are tagged as human clinical trials.
| Recent study | Journal | Date |
|---|---|---|
| Epitalon and Epithalamin: A Narrative Review of Mechanistic, Preclinical, and Clinical Evidence. | Int J Mol Sci | 2026 Oct 8 |
| Synthetic Peptides in Pharmacy Compounding: Analysis of PCAC Recommendations and Industry Safety Standards. | Int J Pharm Compd | 2026 Jul-Aug |
| LCP2 mediates SUV39H1-driven cellular senescence-related chemoresistance in natural killer/T-cell lymphoma. | Cell Death Dis | 2026 May 28 |
| Therapeutic peptides in gerontology: mechanisms and applications for healthy aging. | Front Aging | 2026 |
| Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. | J Am Acad Orthop Surg Glob Res Rev | 2026 Jan 1 |
Sources
This is general research information, not medical advice. Check with a clinician before using any compound.