DSIP (Delta sleep-inducing peptide)
Sleep · By Preptide Pro editorial team · Last updated
DSIP (Delta sleep-inducing peptide) is a sleep peptide, and it is not FDA-approved. A nonapeptide first isolated in the 1970s and studied for effects on sleep. Human study results have been mixed.
Not FDA-approvedChemistry (PubChem)
| PubChem CID | 68816 |
|---|---|
| CAS number | 62568-57-4 |
| Molecular formula | C35H48N10O15 |
| Molecular weight | 848.8 g/mol |
| Other names | Emideltide, DSIP nonapeptide, Emideltide [INN], DELTA SLEEP-INDUCING PEPTIDE, emideltida, Delta sleep-inducing peptide (rabbit), UNII-YN28Z5YZ73, Delta Sleep Peptide |
Is DSIP (Delta sleep-inducing peptide) FDA-approved?
Not FDA-approved. No matching NDA or BLA was found in openFDA (Drugs@FDA).
How much research is there on DSIP (Delta sleep-inducing peptide)?
PubMed lists 518 records for “"delta sleep-inducing peptide"”, of which 19 are tagged as human clinical trials.
| Recent study | Journal | Date |
|---|---|---|
| Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. | J Am Acad Orthop Surg Glob Res Rev | 2026 Jan 1 |
| Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models. | Front Pharmacol | 2024 |
| Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke. | Molecules | 2021 Aug 26 |
| DSIP-Like KND Peptide Reduces Brain Infarction in C57Bl/6 and Reduces Myocardial Infarction in SD Rats When Administered during Reperfusion. | Biomedicines | 2021 Apr 9 |
| Phosphorylated delta sleep inducing peptide restores spatial memory and p-CREB expression by improving sleep architecture at high altitude. | Life Sci | 2018 Sep 15 |
Sources
This is general research information, not medical advice. Check with a clinician before using any compound.