Dihexa
Nootropic · By Preptide Pro editorial team · Last updated
Dihexa is a nootropic peptide, and it is not FDA-approved. A small peptide-derived compound designed to act on the HGF/c-Met pathway. Research so far is in animal models of cognition.
Not FDA-approvedChemistry (PubChem)
| PubChem CID | 129010512 |
|---|---|
| CAS number | 1401708-83-5 |
| Molecular formula | C27H44N4O5 |
| Molecular weight | 504.7 g/mol |
| Other names | dihexa, PNB-0408, ATH-1001, RefChem:1090816, DTXCID001517923, Hexanoyl-Tyr-Ile-Ahx-NH2, UNII-9WYX65A5C2, Dihexa (PNB-0408)? |
Is Dihexa FDA-approved?
Not FDA-approved. No matching NDA or BLA was found in openFDA (Drugs@FDA).
How much research is there on Dihexa?
PubMed lists 19 records for “dihexa”, of which 0 are tagged as human clinical trials.
| Recent study | Journal | Date |
|---|---|---|
| Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. | J Am Acad Orthop Surg Glob Res Rev | 2026 Jan 1 |
| Hepatocyte Growth Factor/MET Activator Rescues Working Memory Deficits after Repeated Mild Traumatic Brain Injury. | Neurotrauma Rep | 2025 |
| Effects of an Angiotensin IV Analog on 3-Nitropropionic Acid-Induced Huntington's Disease-Like Symptoms in Rats. | J Huntingtons Dis | 2024 |
| Efficiently generate functional hepatic cells from human pluripotent stem cells by complete small-molecule strategy. | Stem Cell Res Ther | 2022 Apr 11 |
| AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway. | Brain Sci | 2021 Nov 11 |
Sources
This is general research information, not medical advice. Check with a clinician before using any compound.